Vulval squamous cell carcinoma arising in chronic hidradenitis suppurativa
Identifieur interne : 008079 ( Main/Exploration ); précédent : 008078; suivant : 008080Vulval squamous cell carcinoma arising in chronic hidradenitis suppurativa
Auteurs : K. A. Short ; G. Kalu ; Peter Mortimer (dermatologue) [Royaume-Uni] ; E. M. HigginsSource :
- Clinical and Experimental Dermatology [ 0307-6938 ] ; 2005-09.
Abstract
We report a case of vulval squamous cell carcinoma (SCC) arising in chronic hidradenitis suppurativa (HS). The patient had a complex medical history including a 25‐year‐history of Crohn's disease. In addition she had recently received immunosuppressive therapy for nephrotic syndrome secondary to membranous glomerulonephritis. A painful nodule was noted on the vulva that was clinically very suspicious of SCC. An excision biopsy confirmed the diagnosis. There are few publications in the English literature citing association between HS and the development of SCC. The first report in the English literature of vulval SCC arising in chronic HS was published in 1999. We wish to draw attention to the possibility that patients with HS may develop SCC in lesional skin. A painful lump or ulcer could easily be mistaken for an inflammatory lesion and a low threshold for biopsy is warranted. We suggest constant vigilance with regard to malignant change in ano‐genital HS as the diagnosis can be difficult.
Url:
DOI: 10.1111/j.1365-2230.2005.01875.x
Affiliations:
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S." last="Mortimer">Peter Mortimer (dermatologue)</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Dermatology, St George's Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Higgins, E M" sort="Higgins, E M" uniqKey="Higgins E" first="E. M." last="Higgins">E. M. Higgins</name><affiliation><wicri:noCountry code="subField">Sussex</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical and Experimental Dermatology</title><title level="j" type="alt">CLINICAL EXPERIMENTAL DERMATOLOGY</title><idno type="ISSN">0307-6938</idno><idno type="eISSN">1365-2230</idno><imprint><biblScope unit="vol">30</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="481">481</biblScope><biblScope unit="page" to="483">483</biblScope><biblScope unit="page-count">3</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2005-09">2005-09</date></imprint><idno type="ISSN">0307-6938</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0307-6938</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report a case of vulval squamous cell carcinoma (SCC) arising in chronic hidradenitis suppurativa (HS). The patient had a complex medical history including a 25‐year‐history of Crohn's disease. In addition she had recently received immunosuppressive therapy for nephrotic syndrome secondary to membranous glomerulonephritis. A painful nodule was noted on the vulva that was clinically very suspicious of SCC. An excision biopsy confirmed the diagnosis. There are few publications in the English literature citing association between HS and the development of SCC. The first report in the English literature of vulval SCC arising in chronic HS was published in 1999. We wish to draw attention to the possibility that patients with HS may develop SCC in lesional skin. A painful lump or ulcer could easily be mistaken for an inflammatory lesion and a low threshold for biopsy is warranted. We suggest constant vigilance with regard to malignant change in ano‐genital HS as the diagnosis can be difficult.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement><orgName><li>Université de Londres</li></orgName></list><tree><noCountry><name sortKey="Higgins, E M" sort="Higgins, E M" uniqKey="Higgins E" first="E. M." last="Higgins">E. M. Higgins</name><name sortKey="Kalu, G" sort="Kalu, G" uniqKey="Kalu G" first="G." last="Kalu">G. Kalu</name><name sortKey="Short, K A" sort="Short, K A" uniqKey="Short K" first="K. A." last="Short">K. A. Short</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mortimer, P S" sort="Mortimer, P S" uniqKey="Mortimer P" first="P. S." last="Mortimer">Peter Mortimer (dermatologue)</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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